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Anti-SAP155 (Polyclonal), ALEXA Fluor 594

Anti-SAP155 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSAP155
SpecificityThis antibody reacts specifically with SAP155
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SAP155/SF3B1
Gene ID23451
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Concomitant with splicing catalysis, Due to alternative splicing events, Localized to nuclear speckles and also to the cytoplasm during mitosis, SAP 130, SAP 145 and SAP 155, SAP 155 is a subunit of the SF3B splicing factor, SAP 155 is phosphorylated at its N-terminal Thr-Pro dipeptide motifs by Dyrk1A and cyclin E/Cdk2, SF3B contains the spliceosomal proteins SAP 49, The SF3B splicing factor is a U2 snRNP-associated protein complex essential for spliceosome assembly, This modification of SAP 155 is vital for a functional spliceosome as it is an essential event in the basic splicing reaction, various SAP 155 isoforms are produced, 304 amino acid member of the SF3B1 family and contains eleven HEAT repeats, SAP 155 is a 1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SAP155 SF3b155 PRPF10 Prp10 Hsh155
Also known asSAP155 Polyclonal Antibody
Other nameAnti-SAP155 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSAP155
Short nameAnti-SAP155 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SAP155 (polyclonal)
Alternative techniquepolyclonals
Identity 10768
Gene SF3B1
Long gene name splicing factor 3b subunit 1
Synonyms gene name 155kD splicing factor 3b, 155kDa , splicing factor 3b, subunit 1, subunit 1
Locus 2q33, 1
Discovery year 2000-02-29
GenBank acession AF054284
Entrez gene record 23451
Pubmed identfication 9585501
Havana BLAST/BLAT OTTHUMG00000154447
Locus Specific Databases LRG_624

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