Name : Anti-SAP155 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8341729513
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SAP155 |
| Specificity | This antibody reacts specifically with SAP155 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human SAP155/SF3B1 |
| Gene ID | 23451 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Concomitant with splicing catalysis, Due to alternative splicing events, Localized to nuclear speckles and also to the cytoplasm during mitosis, SAP 130, SAP 145 and SAP 155, SAP 155 is a subunit of the SF3B splicing factor, SAP 155 is phosphorylated at its N-terminal Thr-Pro dipeptide motifs by Dyrk1A and cyclin E/Cdk2, SF3B contains the spliceosomal proteins SAP 49, The SF3B splicing factor is a U2 snRNP-associated protein complex essential for spliceosome assembly, This modification of SAP 155 is vital for a functional spliceosome as it is an essential event in the basic splicing reaction, various SAP 155 isoforms are produced, 304 amino acid member of the SF3B1 family and contains eleven HEAT repeats, SAP 155 is a 1 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | SAP155 SF3b155 PRPF10 Prp10 Hsh155 |
| Also known as | SAP155 Polyclonal Antibody |
| Other name | Anti-SAP155 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SAP155 |
| Short name | Anti-SAP155 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-SAP155 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 10768 |
| Gene | SF3B1 |
| Long gene name | splicing factor 3b subunit 1 |
| Synonyms gene name | 155kD splicing factor 3b, 155kDa , splicing factor 3b, subunit 1, subunit 1 |
| Locus | 2q33, 1 |
| Discovery year | 2000-02-29 |
| GenBank acession | AF054284 |
| Entrez gene record | 23451 |
| Pubmed identfication | 9585501 |
| Havana BLAST/BLAT | OTTHUMG00000154447 |
| Locus Specific Databases | LRG_624 |