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Anti-Scavenger Receptor BII, ALEXA Fluor 594

Anti-Scavenger Receptor BII, ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideScavenger Receptor BII
SpecificityThis antibody reacts specifically with Scavenger Receptor BII
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsHelical
Antigen SourceKLH conjugated synthetic peptide derived from human Scavenger Receptor BII
Gene ID950
Swiss ProtQ14108
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Although the role of these scavenger receptors is not completely clear, Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, SR-BI and SR-BII (previously known as SR-BI, SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues, SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells, Therefore, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells, 2) are the alternatively spliced products of a single gene, High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Cav2, 3 BII CACH6
Also known asScavenger Receptor BII Antibody
Other nameAnti-Scavenger Receptor BII
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetScavenger Receptor BII
Short name Fluor 594, Anti-Scavenger Receptor BII
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Scavenger Receptor BII
Identity 1392
Gene CACNA1E
Long gene name calcium voltage-gated channel subunit alpha1 E
Synonyms gene CACNL1A6
Synonyms gene name R type, alpha 1E subunit calcium voltage-gated channel subunit alpha1 subunit E , calcium channel, voltage-dependent
Locus 1q25, 3
Discovery year 1994-12-20
GenBank acession AK096563
Entrez gene record 777
Pubmed identfication 8388125 16382099
RefSeq identity NM_000721
Classification Calcium voltage-gated channel subunits EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000037301

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