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Anti-SCN2B (Polyclonal), ALEXA Fluor 594

Anti-SCN2B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSCN2B
SpecificityThis antibody reacts specifically with SCN2B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human SCN2B
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information During the propagation of an action potential, Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23, Na+ CP type II beta(sodium channel, also known as SCN2B, beta), is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier, sodium channels allow an influx of sodium ions, type II, voltage-gated, which rapidly depolarizes the cell, 2, 3 and mouse chromosome 9 A5, Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asSCN2B Polyclonal Antibody
Other nameAnti-SCN2B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSCN2B
Short nameAnti-SCN2B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SCN2B (polyclonal)
Alternative techniquepolyclonals
Identity 10589
Gene SCN2B
Long gene name sodium voltage-gated channel beta subunit 2
Synonyms gene name beta polypeptide sodium channel, beta sodium channel, beta subunit sodium channel, sodium channel, type II, type II, type II, type II beta subunit , voltage gated, voltage-gated, voltage-gated, voltage-gated
Locus 11q23, 3
Discovery year 1988-11-28
GenBank acession AY358945
Entrez gene record 6327
Pubmed identfication 10198179
RefSeq identity NM_004588
Classification Sodium voltage-gated channel beta subunits V-set domain containing
Havana BLAST/BLAT OTTHUMG00000048248

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