Name : Anti-SCN2B (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5256295869
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SCN2B |
| Specificity | This antibody reacts specifically with SCN2B |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human SCN2B |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | During the propagation of an action potential, Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23, Na+ CP type II beta(sodium channel, also known as SCN2B, beta), is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier, sodium channels allow an influx of sodium ions, type II, voltage-gated, which rapidly depolarizes the cell, 2, 3 and mouse chromosome 9 A5, Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | SCN2B Polyclonal Antibody |
| Other name | Anti-SCN2B Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SCN2B |
| Short name | Anti-SCN2B (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-SCN2B (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 10589 |
| Gene | SCN2B |
| Long gene name | sodium voltage-gated channel beta subunit 2 |
| Synonyms gene name | beta polypeptide sodium channel, beta sodium channel, beta subunit sodium channel, sodium channel, type II, type II, type II, type II beta subunit , voltage gated, voltage-gated, voltage-gated, voltage-gated |
| Locus | 11q23, 3 |
| Discovery year | 1988-11-28 |
| GenBank acession | AY358945 |
| Entrez gene record | 6327 |
| Pubmed identfication | 10198179 |
| RefSeq identity | NM_004588 |
| Classification | Sodium voltage-gated channel beta subunits V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000048248 |