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Anti-SCN8A (Polyclonal), ALEXA Fluor 594

Anti-SCN8A (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSCN8A
SpecificityThis antibody reacts specifically with SCN8A
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen Source6, KLH conjugated synthetic peptide derived from human SCN8A/Nav1
Gene ID6334
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Assuming opened or closed conformations in response to the voltage difference across the membrane, In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient, Mediates the voltage-dependent sodium ion permeability of excitable membranes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Nav1, 6 NaCh6 PN4 CerIII
Also known asSCN8A Polyclonal Antibody
Other nameAnti-SCN8A Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSCN8A
Short nameAnti-SCN8A (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SCN8A (polyclonal)
Alternative techniquepolyclonals
Identity 10596
Gene SCN8A
Long gene name sodium voltage-gated channel alpha subunit 8
Synonyms gene MED
Synonyms gene name alpha polypeptide sodium channel, alpha subunit sodium channel, sodium channel, type VIII, type VIII, type VIII alpha subunit , voltage gated, voltage gated, voltage gated
Locus 12q13, 1
Discovery year 1995-08-23
GenBank acession AB027567
Entrez gene record 6334
Pubmed identfication 7670495 9828131 16382098
RefSeq identity NM_014191
Classification Sodium voltage-gated channel alpha subunits
Havana BLAST/BLAT OTTHUMG00000169490

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