Name : Anti-SCNN1B(Ser633) (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN9110422312
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SCNN1B Ser633 |
| Specificity | This antibody reacts specifically with SCNN1B(Ser633) |
| Modification | Phosphorylation |
| Modification site | Ser633 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Cytoplasm |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human SCNN1B around the phosphorylation site of Ser633 |
| Gene ID | 6338 |
| Swiss Prot | P51168 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Also plays a role in taste perception, Controls the reabsorption of sodium in kidney, Mediates the electrodiffusion of the luminal sodium (and water, Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, colon, lung and sweat glands, which follows osmotically) through the apical membrane of epithelial cells, which is important for proper clearance of mucus, Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | ENaCbeta |
| Also known as | SCNN1B(Ser633) Polyclonal Antibody |
| Other name | Anti-SCNN1B(Ser633) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SCNN1B(Ser633) |
| Short name | Anti-SCNN1B(Ser633) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-SCNN1B(Ser633) (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 10600 |
| Gene | SCNN1B |
| Long gene name | sodium channel epithelial 1 beta subunit |
| Synonyms gene name | beta sodium channel, beta sodium channel, beta subunit sodium channel, non voltage gated 1 beta subunit , non-voltage-gated 1, non-voltage-gated 1, nonvoltage-gated 1, sodium channel |
| Synonyms name | Liddle syndrome |
| Locus | 16p12, 1 , 2-p12 |
| Discovery year | 1994-12-20 |
| GenBank acession | X87159 |
| Pubmed identfication | 26772908 |
| Classification | Sodium channels epithelial |
| Havana BLAST/BLAT | OTTHUMG00000131608 |
| Locus Specific Databases | LOVD - Leiden Open Variation Database |