Name : Anti-SCRO (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5466148123
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SCRO |
| Specificity | This antibody reacts specifically with SCRO |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human SCRO/DCUN1D1 |
| Gene ID | 54165 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Acts also as an oncogene facilitating malignant transformation and carcinogenic progression, Defects in DCUN1D1 may be a cause of squamous cell carcinomas, Forms part of an E3 ubiquitin ligase complex for neddylation, Functions to recruit the NEDD8-charged E2 enzyme to the cullin component, Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity, Not overexpressed in aggressive adrenocortical carcinomas, Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation, and malignant tissues of squamous cell carcinoma of the oral tongue, bronchioloalveolar carcinomas, DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin, Strongly overexpressed in thyroid tumors |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | RP42 SCRO DCUN1L1 Tes3 SCCRO |
| Also known as | SCRO Polyclonal Antibody |
| Other name | Anti-SCRO Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SCRO |
| Short name | Anti-SCRO (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-SCRO (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 18184 |
| Gene | DCUN1D1 |
| Long gene name | defective in cullin neddylation 1 domain containing 1 |
| Synonyms gene name | DCN1, cerevisiae) , defective in cullin neddylation 1, domain containing 1 (S |
| Synonyms name | squamous cell carcinoma related oncogene |
| Locus | 3q26, 33 |
| Discovery year | 2005-07-11 |
| GenBank acession | AF292100 AK056335 |
| Entrez gene record | 54165 |
| Pubmed identfication | 10777668 15988528 |
| RefSeq identity | NM_020640 |
| Havana BLAST/BLAT | OTTHUMG00000158314 |