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Anti-SCRO (Polyclonal), ALEXA Fluor 594

Anti-SCRO (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSCRO
SpecificityThis antibody reacts specifically with SCRO
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SCRO/DCUN1D1
Gene ID54165
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts also as an oncogene facilitating malignant transformation and carcinogenic progression, Defects in DCUN1D1 may be a cause of squamous cell carcinomas, Forms part of an E3 ubiquitin ligase complex for neddylation, Functions to recruit the NEDD8-charged E2 enzyme to the cullin component, Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity, Not overexpressed in aggressive adrenocortical carcinomas, Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation, and malignant tissues of squamous cell carcinoma of the oral tongue, bronchioloalveolar carcinomas, DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin, Strongly overexpressed in thyroid tumors
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms RP42 SCRO DCUN1L1 Tes3 SCCRO
Also known asSCRO Polyclonal Antibody
Other nameAnti-SCRO Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSCRO
Short nameAnti-SCRO (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SCRO (polyclonal)
Alternative techniquepolyclonals
Identity 18184
Gene DCUN1D1
Long gene name defective in cullin neddylation 1 domain containing 1
Synonyms gene name DCN1, cerevisiae) , defective in cullin neddylation 1, domain containing 1 (S
Synonyms name squamous cell carcinoma related oncogene
Locus 3q26, 33
Discovery year 2005-07-11
GenBank acession AF292100 AK056335
Entrez gene record 54165
Pubmed identfication 10777668 15988528
RefSeq identity NM_020640
Havana BLAST/BLAT OTTHUMG00000158314

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