Name : Anti-Sec8 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8210651827
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Sec8 |
| Specificity | This antibody reacts specifically with Sec8 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Sec8 |
| Gene ID | 60412 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Exo70 and Exo84, Human Sec8 maps to chromosome 7q33, It is crucial for cell-cell communication, REC8 or SEC8L1, Sec10, Sec15, Sec5, Sec6, Sec8, Sec8, The exocyst complex inhibits tubulin polymerization in vitro, The exocyst complex is a multi-protein complex that consists of Sec3, also known as EXOC4 (exocyst complex component 4), and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane, as well as the incorporation of membrane proteins and lipids to the plasma membrane, cell growth and cell polarity, is one of eight protein subunits composing the mammalian exocyst complex, suggesting that the exocyst complex is important for modulating the microtubule dynamics that underlie exocytosis, Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA1699 MGC27170 SEC8 Sec8p |
| Also known as | Sec8 Polyclonal Antibody |
| Other name | Anti-Sec8 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Sec8 |
| Short name | Anti-Sec8 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Sec8 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 30389 |
| Gene | EXOC4 |
| Long gene name | exocyst complex component 4 |
| Synonyms gene | SEC8L1 |
| Synonyms gene name | SEC8-like 1 (S, cerevisiae) |
| Locus | 7q33 |
| Discovery year | 2004-01-08 |
| GenBank acession | AL831989 |
| Entrez gene record | 60412 |
| Pubmed identfication | 11214970 12687004 |
| RefSeq identity | NM_021807 |
| Classification | Exocyst complex |
| Havana BLAST/BLAT | OTTHUMG00000155259 |