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Anti-Sema4C (Polyclonal), ALEXA Fluor 594

Anti-Sema4C (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSema4C
SpecificityThis antibody reacts specifically with Sema4C
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human Sema4C
Gene ID9037
Swiss ProtQ13591
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In glioma cells, Ligand for receptor PLXNB3, May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1, while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity), Bifunctional axonal guidance cue regulated by sulfated proteoglycans
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Semacl1 Semaf
Also known asSema4C Polyclonal Antibody
Other nameAnti-Sema4C Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSema4C
Short nameAnti-Sema4C (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name (semaphorin) 4C (polyclonal), ALEXA Fluor 594, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, antibody to-sema domain
Alternative techniquepolyclonals
Identity 10731
Gene SEMA4C
Long gene name semaphorin 4C
Synonyms gene SEMAI
Synonyms gene name (semaphorin) 4C , immunoglobulin domain (Ig), sema domain, transmembrane domain (TM) and short cytoplasmic domain
Synonyms name M-Sema F
Locus 2q11, 2
Discovery year 2004-02-04
GenBank acession AB051526
Entrez gene record 54910
Pubmed identfication 7656991
RefSeq identity NM_017789
Classification Semaphorins Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000130535

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