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Anti-SERPINA12 (Polyclonal), ALEXA Fluor 594

Anti-SERPINA12 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSERPINA12
SpecificityThis antibody reacts specifically with SERPINA12
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SERPINA12/Vaspin
Gene ID145264
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A number of such serpins have been shown to target cysteine proteases, It may modulates insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues, Most inhibitory serpins target chymotrypsin-like serine proteases, Most serpins control proteolytic cascades, SerpinA12, SerpinA12 / Vaspin is expressed in visceral adipose tissues, SerpinA12 / Vaspin may be the compensatory molecule in the pathogenesis of metabolic syndrome and SerpinA12 / Vaspin recombinant protein or vaspin-mimicking agents such as vaspin analogs, Some serpins inhibit other classes of protease, These enzymes are defined by the presence of a nucleophilic serine residue in their catalytic site, These enzymes differ from serine proteases in that they are defined by the presence of a nucleophilic cysteine residue, Vaspin, Visceral adipose tissue-derived serine protease inhibitor, Visceral adipose-specific serpin and SERPINA12, also known as OL-64, but instead perform diverse functions such as storage (ovalbumin, certain serpins do not inhibit enzymes, cortisol-binding globulin) and tumor suppressor genes (maspin), hormone carriage proteins (thyroxine-binding globulin, in egg white), in their catalytic site, is a secreted protein which belongs to the serpin family, or small molecule agents may be the link to drug discovery and development, rather than a serine residue, May modulates insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues, Serpins are the largest and most diverse family of protease inhibitors
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms OL-64 Vaspin
Also known asSERPINA12 Polyclonal Antibody
Other nameAnti-SERPINA12 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSERPINA12
Short nameAnti-SERPINA12 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SERPINA12 (polyclonal)
Alternative techniquepolyclonals
Identity 18359
Gene SERPINA12
Long gene name serpin family A member 12
Synonyms gene name antitrypsin), antitrypsin), clade A (alpha-1 antiproteinase, clade A (alpha-1 antiproteinase, member 12 , member 12 serpin peptidase inhibitor, serine (or cysteine) proteinase inhibitor
Locus 14q32, 13
Discovery year 2004-05-21
GenBank acession AY177692
Entrez gene record 145264
Pubmed identfication 24172014
RefSeq identity NM_173850
Classification Serpin peptidase inhibitors
Havana BLAST/BLAT OTTHUMG00000171349

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