Name : Anti-SERPINB1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8881147516
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SERPINB1 |
| Specificity | This antibody reacts specifically with SERPINB1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human SERPINB1 |
| Gene ID | 1992 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Human SerpinB1, SERPINB1, SerpinB1b, SerpinB1c and the pseudogene, Serpinb1-ps1, Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease, The monocyte/neutrophil elastase inhibitor gene, The three protein-coding genes share significant sequence identity, There are four homologous genes in mouse designated SerpinB1a, also designated monocyte/neutrophil elastase inhibitor (M/NEI) or leukocyte elastase inhibitor (LEI), belongs to the Ov-serpin family (ovalbumin-related serpins), cathepsin-G and proteinase-3, complement activation, however SerpinB1a (also designated EIA) has been characterized as the functional ortholog of human SerpinB1, including the control of blood coagulation, is a cytoplasmic protein which acts as a fast-acting stoichiometric proteinase inhibitor that regulates the activity of neutrophil elastase (NE), programmed cell death and development, The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | EI PI2 anti-elastase |
| Also known as | SERPINB1 Polyclonal Antibody |
| Other name | Anti-SERPINB1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SERPINB1 |
| Short name | Anti-SERPINB1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-SERPINB1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 3311 |
| Gene | SERPINB1 |
| Long gene name | serpin family B member 1 |
| Synonyms gene | ELANH2 |
| Synonyms gene name | clade B (ovalbumin), clade B (ovalbumin), member 1 , member 1 serpin peptidase inhibitor, serine (or cysteine) proteinase inhibitor |
| Locus | 6p25, 2 |
| Discovery year | 1993-07-27 |
| GenBank acession | M93056 |
| Entrez gene record | 1992 |
| Pubmed identfication | 1376927 24172014 |
| Classification | Serpin peptidase inhibitors |
| Havana BLAST/BLAT | OTTHUMG00000014124 |