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Anti-SGSH/Sulphamidase (Polyclonal), ALEXA Fluor 594

Anti-SGSH/Sulphamidase (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSGSH/Sulphamidase
SpecificityThis antibody reacts specifically with SGSH/Sulphamidase
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsLysosome
Antigen SourceKLH conjugated synthetic peptide derived from human Sulphamidase
Gene ID6448
Swiss ProtP51688
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the gene encoding sulfamidase are the cause of Sanfilippo syndrome A, Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids, It has been suggested that sulfamidase may be involved in the lysosomal degradation of heparan sulfate, MPS3A or SGSH, SFMD, Sanfilippo syndrome A is characterized by severe central nervous system degeneration but relatively mild somatic manifestations, Sulfamidase, also known as HSS, an autosomal recessive lysosomal storage disease caused by impaired degradation of heparan sulfate, is a 502 amino acid lysosome that belongs to the sulfatase family, Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HSS MPS3A SFMD
Also known asSGSH/Sulphamidase Polyclonal Antibody
Other nameAnti-SGSH/Sulphamidase Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSGSH/Sulphamidase
Short nameAnti-SGSH/Sulphamidase (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SGSH/Sulphamidase (polyclonal)
Alternative techniquepolyclonals
Identity 10818
Gene SGSH
Long gene name N-sulfoglucosamine sulfohydrolase
Synonyms name sulfamidase mucopolysaccharidosis type IIIA
Locus 17q25, 3
Discovery year 1997-06-24
GenBank acession BC047318
Entrez gene record 6448
Pubmed identfication 7493035
RefSeq identity NM_000199
Classification Sulfatases
Havana BLAST/BLAT OTTHUMG00000177569

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