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Anti-SHFM3 (Polyclonal), ALEXA Fluor 594

Anti-SHFM3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSHFM3
SpecificityThis antibody reacts specifically with SHFM3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SHFM3
Gene ID6468
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Likely to be involved in key signaling pathways crucial for normal limb development, May participate in Wnt signaling, SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits, Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) , Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Fbw4 dactylin
Also known asSHFM3 Polyclonal Antibody
Other nameAnti-SHFM3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSHFM3
Short nameAnti-SHFM3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SHFM3 (polyclonal)
Alternative techniquepolyclonals
Identity 10847
Gene FBXW4
Long gene name F-box and WD repeat domain containing 4
Synonyms gene SHFM3
Synonyms gene name split hand/foot malformation (ectrodactyly) type 3 F-box and WD-40 domain protein 4
Locus 10q24, 32
Discovery year 1994-09-26
GenBank acession AF281859
Entrez gene record 6468
Pubmed identfication 8723077 7912888
RefSeq identity NM_022039
Classification F-box and WD repeat domain containing WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000018938

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