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Anti-Shh (Polyclonal), ALEXA Fluor 594

Anti-Shh (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideShh
SpecificityThis antibody reacts specifically with Shh
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCell membrane
Antigen SourceKLH conjugated synthetic peptide derived from human Shh
Gene ID6469
Swiss ProtQ15465
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity), Displays both floor plate- and motor neuron-inducing activity, The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud, Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HHG1 SMMCI TPT TPTPS MCOPCB5
Also known asShh Polyclonal Antibody
Other nameAnti-Shh Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetShh
Short nameAnti-Shh (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-sonic hedgehog (polyclonal)
Alternative techniquepolyclonals
Identity 10848
Gene SHH
Long gene name sonic hedgehog
Synonyms gene HPE3 HLP3
Synonyms gene name sonic hedgehog (Drosophila) homolog sonic hedgehog homolog (Drosophila)
Locus 7q36, 3
Discovery year 1995-03-10
Entrez gene record 6469
Pubmed identfication 7590746
RefSeq identity NM_000193
Havana BLAST/BLAT OTTHUMG00000151349

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