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Anti-SHIP1 (Polyclonal), ALEXA Fluor 594

Anti-SHIP1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSHIP1
SpecificityThis antibody reacts specifically with SHIP1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SHIP1
Gene ID3635
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information At the plasma membrane, Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation, Overall the protein functions as a negative regulator of myeliod cell proliferation and survival, an inositol phosphatase domain, and two C-terminal protein interaction domains, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3, thereby affecting multiple signaling pathways, 3, 4, 4, 5)-trisphosphate and inositol-1, 5-tetrakisphosphate, SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SHIP hp51CN SHIP1
Also known asSHIP1 Polyclonal Antibody
Other nameAnti-SHIP1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSHIP1
Short nameAnti-SHIP1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SHIP1 (polyclonal)
Alternative techniquepolyclonals
Identity 6079
Gene INPP5D
Long gene name inositol polyphosphate-5-phosphatase D
Synonyms gene name 145kD inositol polyphosphate-5-phosphatase, 145kDa , inositol polyphosphate-5-phosphatase
Synonyms name SH2 domain-containing inositol 5', -phosphatase 1
Locus 2q37, 1
Discovery year 1996-04-04
GenBank acession U57650
Entrez gene record 3635
Pubmed identfication 8643691 8874179
RefSeq identity NM_001017915
Classification Phosphoinositide phosphatases SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000133688

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