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Anti-SIP1 (Polyclonal), ALEXA Fluor 594

Anti-SIP1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSIP1
SpecificityThis antibody reacts specifically with SIP1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human SIP1
Gene ID9839
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR), Patients with SIP1 mutations show mental retardation, SIP1, SIP1, SIP1 contains a SMAD-binding domain, SIP1 plays a crucial role in normal embryonic development of neural structures and the neural crest, The human SIP1 gene maps to chromosome 2q22, ZFHX1B and ZEB2 (zinc finger E-box-binding protein 2), a homeodomain and two clusters of zinc fingers on the N- and C-termini, also known as SMADIP1, can be induced by TGFâ, delayed motor development, distinct facial features and/or congenital heart diseaseâ, epilepsy, for SMAD interacting protein 1, is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins, microcephaly, treatment, &circ, &euro, «, &rdquo, SMAD regulates gene expression by interacting with different classes of transcription factors including DNA-binding multi-zinc finger proteins, all symptoms of HSCR
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asSIP1 Polyclonal Antibody
Other nameAnti-SIP1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSIP1
Short nameAnti-SIP1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SIP1 (polyclonal)
Alternative techniquepolyclonals
Identity 10884
Gene GEMIN2
Long gene name gem nuclear organelle associated protein 2
Synonyms gene SIP1
Synonyms gene name survival of motor neuron protein interacting protein 1 gem (nuclear organelle) associated protein 2
Locus 14q21, 1
Discovery year 1998-10-16
GenBank acession AF027150
Entrez gene record 8487
Pubmed identfication 9323130 9323129 11121410
Classification Gemins
Havana BLAST/BLAT OTTHUMG00000028816

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