Name : Anti-SIPA1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7365542531
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SIPA1 |
| Specificity | This antibody reacts specifically with SIPA1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human SIPA1 |
| Gene ID | 6494 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Expressed abundantly in the lymphoid tissues such as thymus, converting it to the putatively inactive GDP-bound state, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord, GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, Tissue specificity: Expressed in fetal as well as in adult tissues |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | SPA1 |
| Also known as | SIPA1 Polyclonal Antibody |
| Other name | Anti-SIPA1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SIPA1 |
| Short name | Anti-SIPA1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-signal-induced proliferation-associated 1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | Rap GTPase activator activity, SIPA1 and IDBG-242018 and ENSG00000213445 and 6494, SIPA1 and IDBG-644217 and ENSBTAG00000013884 and 508234, SPA1, Sipa1 and IDBG-132413 and ENSMUSG00000056917 and 20469, nuclei, this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0007010 and cytoskeleton organization and biological process this GO :0007162 and negative regulation of cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0030133 and transport vesicle and cellular component this GO :0030308 and negative regulation of cell growth and biological process this GO :0032854 and positive regulation of Rap GTPase activity and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042631 and cellular response to water deprivation and biological process this GO :0043234 and protein complex and cellular component this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0046582 and Rap GTPase activator activity and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051726 and regulation of cell cycle and biological process, this GO :0005096: GTPase activator activity, this GO :0005096: GTPase activator activity and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding and also this GO :0046582: Rap GTPase activator activity, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, this GO :0046582: Rap GTPase activator activity, signal-induced proliferation-associated 1 |
| Identity | 10885 |
| Gene | SIPA1 |
| Long gene name | signal-induced proliferation-associated 1 |
| Locus | 11q13, 1 |
| Discovery year | 1997-12-23 |
| GenBank acession | AH006363 BC010492 BM677738 |
| Entrez gene record | 6494 |
| Pubmed identfication | 9027487 |
| RefSeq identity | NM_006747 |
| Classification | PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000166541 |