Name : Anti-SLAMF1(Tyr281) (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN2958667395
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SLAMF1 Tyr281 |
| Specificity | This antibody reacts specifically with SLAMF1(Tyr281) |
| Modification | Phosphorylation |
| Modification site | Tyr281 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human SLAMF1 around the phosphorylation site of Tyr281 |
| Gene ID | 6504 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Activated B cells express the membrane bound form of SLAM and the soluble and cytoplasmic isoforms of SLAM, It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells, Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells, SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, a novel glycoprotein of 37kDa, and a proportion of B cells, and is rapidly induced on naive T cells after activation, and the expression levels of membrane bound SLAM on B cells are rapidly regulated after activation in vitro, belongs to the immunoglobulin gene superfamily and is involved in T cell stimulation, designated SLAM (Signaling Lymphocyte Activation Molecule) or CDw150, immature thymocytes, SLAM |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CD150 |
| Also known as | SLAMF1(Tyr281) Polyclonal Antibody |
| Other name | Anti-SLAMF1(Tyr281) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SLAMF1(Tyr281) |
| Short name | Anti-SLAMF1(Tyr281) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-signaling lymphocytic activation molecule family member 1(Tyr281) (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | CD150 and CDw150 and SLAM, Cell surfaces, SLAMF1 and IDBG-104073 and ENSG00000117090 and 6504, SLAMF1 and IDBG-630529 and ENSBTAG00000007927 and 281489, Slamf1 and IDBG-204832 and ENSMUSG00000015316 and 27218, protein binding, this GO :0003823 and antigen binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0007165 and signal transduction and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031338 and regulation of vesicle fusion and biological process this GO :0045087 and innate immune response and biological process this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0046649 and lymphocyte activation and biological process this GO :0050790 and regulation of catalytic activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0003823: antigen binding, this GO :0003823: antigen binding and also this GO :0004872: receptor activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding, this GO :0004872: receptor activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005515: protein binding, signaling lymphocytic activation molecule family member 1 |
| Identity | 10903 |
| Gene | SLAMF1 |
| Long gene name | signaling lymphocytic activation molecule family member 1 |
| Synonyms gene | SLAM |
| Synonyms gene name | signaling lymphocytic activation molecule |
| Locus | 1q23, 3 |
| Discovery year | 1998-08-06 |
| GenBank acession | U33017 |
| Entrez gene record | 6504 |
| Pubmed identfication | 7617038 |
| Classification | CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT | OTTHUMG00000024006 |