Anti-SLAP (Polyclonal), ALEXA Fluor 594

Anti-SLAP (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	SLAP
Specificity	This antibody reacts specifically with SLAP
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human SLAP
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	3BP1 has been identified as a protein with a high affinity proline-rich binding site for the SH3 domain of c-Abl p120, A similar putative adapter protein, Deletion or mutation of SH3 domains generally activate the transforming potential of nonreceptor tyrosine kinases, In general, SH3 domains are often accompanied by SH2 domains of 100 amino acids, Slap contains a single SH2 and SH3 domain that exhibits homology with those from members of the Src kinase family, The N- and C-termini, The functions of SH3 domains are not as well defined, and in small adapter proteins, are unique, as in the nonreceptor protein-tyrosine kinases and phospholipase C-? within structural proteins, designated Slap, for Src-like adapter protein, frequently linking activated growth factors to putative signal transduction proteins, has been cloned, however, it exists in association with catalytic domains, such as Crk and GRB2, such as spectrin or Myosin, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity, which bind to tyrosine-phosphorylated regions of target proteins, The Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	SLAP KIAA1601
Also known as	SLAP Polyclonal Antibody
Other name	Anti-SLAP Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	SLAP
Short name	Anti-SLAP (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-SLAP (polyclonal)
Alternative technique	polyclonals
Identity	16643
Gene	SLMAP
Long gene name	sarcolemma associated protein
Synonyms name	Sarcolemmal-associated protein
Locus	3p14, 3
Discovery year	2001-12-03
GenBank acession	AF100750
Entrez gene record	7871
Pubmed identfication	9405447 11042152
RefSeq identity	NM_007159
Classification	STRIPAK complex
Havana BLAST/BLAT	OTTHUMG00000133764

Anti-SLAP (Polyclonal), ALEXA Fluor 594

Anti-SLAP (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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