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Anti-SLC25A12/ARALAR (Polyclonal), ALEXA Fluor 594

Anti-SLC25A12/ARALAR (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSLC25A12/ARALAR
SpecificityThis antibody reacts specifically with SLC25A12/ARALAR
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SLC25A12/ARALAR
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ARALAR, ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle, ARALAR is implicated in conferring susceptibility to schizophrenia, ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation, In addition, It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH, Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS), the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Aralar
Also known asSLC25A12/ARALAR Polyclonal Antibody
Other nameAnti-SLC25A12/ARALAR Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSLC25A12/ARALAR
Short nameAnti-SLC25A12/ARALAR (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SLC25A12/ARALAR (polyclonal)
Alternative techniquepolyclonals
Identity 10982
Gene SLC25A12
Long gene name solute carrier family 25 member 12
Synonyms gene name Aralar), member 12 , member 12 solute carrier family 25 (aspartate/glutamate carrier), solute carrier family 25 (mitochondrial carrier
Locus 2q31, 1
Discovery year 1999-01-28
GenBank acession Y14494
Entrez gene record 8604
Pubmed identfication 9722566 10702666 11566871
RefSeq identity NM_003705
Classification Solute carriers EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000134290

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