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Anti-SLC5A8 (Polyclonal), ALEXA Fluor 594

Anti-SLC5A8 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSLC5A8
SpecificityThis antibody reacts specifically with SLC5A8
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human SLC5A8
Gene ID160728
Swiss ProtQ8N695
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts as a tumor suppressor, Catalyzes passive carrier mediated diffusion of iodide, D-lactate, May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract, May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons, Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane, acetate, acetoacetate and alpha-ketoisocaproate), benzoate, including transport of monocarboxylates (short-chain fatty acids including L-lactate, lactate, mocarboxylate drugs (nicotinate, propionate, prostate cancer and glioma cell lines, pyruvate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, suppressing colony formation in colon cancer, valerate and butyrate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1, Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms AIT
Also known asSLC5A8 Polyclonal Antibody
Other nameAnti-SLC5A8 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSLC5A8
Short nameAnti-SLC5A8 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, member 8 (polyclonal), antibody to-solute carrier family 5 (iodide transporter)
Alternative techniquepolyclonals
Alternative to gene target Plasma membranes, SLC5A8 and IDBG-547244 and ENSG00000256870 and 160728, SMCT1 and IDBG-636931 and ENSBTAG00000011525 and 615734, Slc5a8 and IDBG-183999 and ENSMUSG00000020062 and 216225, member 8, symporter activity, this GO :0005215 and transporter activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006810 and transport and biological process this GO :0006811 and ion transport and biological process this GO :0006814 and sodium ion transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0015293 and symporter activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0055085 and transmembrane transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005215: transporter activity, this GO :0005215: transporter activity and also this GO :0015293: symporter activity, this GO :0015293: symporter activity, solute carrier family 5 (iodide transporter)
Identity 19119
Gene SLC5A8
Long gene name solute carrier family 5 member 8
Synonyms gene name member 8 , member 8 solute carrier family 5 (sodium/monocarboxylate cotransporter), solute carrier family 5 (iodide transporter)
Locus 12q23, 1-q23, 2
Discovery year 2003-05-12
GenBank acession AY081220
Entrez gene record 160728
Pubmed identfication 12107270 12829793
RefSeq identity NM_145913
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000170499

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