Name : Anti-SLC5A8 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3606602939
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SLC5A8 |
| Specificity | This antibody reacts specifically with SLC5A8 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human SLC5A8 |
| Gene ID | 160728 |
| Swiss Prot | Q8N695 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Acts as a tumor suppressor, Catalyzes passive carrier mediated diffusion of iodide, D-lactate, May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract, May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons, Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane, acetate, acetoacetate and alpha-ketoisocaproate), benzoate, including transport of monocarboxylates (short-chain fatty acids including L-lactate, lactate, mocarboxylate drugs (nicotinate, propionate, prostate cancer and glioma cell lines, pyruvate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, suppressing colony formation in colon cancer, valerate and butyrate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1, Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | AIT |
| Also known as | SLC5A8 Polyclonal Antibody |
| Other name | Anti-SLC5A8 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SLC5A8 |
| Short name | Anti-SLC5A8 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, member 8 (polyclonal), antibody to-solute carrier family 5 (iodide transporter) |
| Alternative technique | polyclonals |
| Alternative to gene target | Plasma membranes, SLC5A8 and IDBG-547244 and ENSG00000256870 and 160728, SMCT1 and IDBG-636931 and ENSBTAG00000011525 and 615734, Slc5a8 and IDBG-183999 and ENSMUSG00000020062 and 216225, member 8, symporter activity, this GO :0005215 and transporter activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006810 and transport and biological process this GO :0006811 and ion transport and biological process this GO :0006814 and sodium ion transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0015293 and symporter activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0055085 and transmembrane transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005215: transporter activity, this GO :0005215: transporter activity and also this GO :0015293: symporter activity, this GO :0015293: symporter activity, solute carrier family 5 (iodide transporter) |
| Identity | 19119 |
| Gene | SLC5A8 |
| Long gene name | solute carrier family 5 member 8 |
| Synonyms gene name | member 8 , member 8 solute carrier family 5 (sodium/monocarboxylate cotransporter), solute carrier family 5 (iodide transporter) |
| Locus | 12q23, 1-q23, 2 |
| Discovery year | 2003-05-12 |
| GenBank acession | AY081220 |
| Entrez gene record | 160728 |
| Pubmed identfication | 12107270 12829793 |
| RefSeq identity | NM_145913 |
| Classification | Solute carriers |
| Havana BLAST/BLAT | OTTHUMG00000170499 |