Name : Anti-SLFN14 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8515533868
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SLFN14 |
| Specificity | This antibody reacts specifically with SLFN14 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human SLFN14 |
| Gene ID | 342618 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence, Slfn1, Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family, Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12, The prototype member of the Schlafen family, These proteins all contain a largely conserved core domain within the center of the sequence, and the induction of Slfn1 induces a G0/G1 arrest, and yet they are substantially diversified at the N terminus, is transcriptionally unregulated during thymocyte positive selection, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis, Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | SLFN14 Polyclonal Antibody |
| Other name | Anti-SLFN14 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SLFN14 |
| Short name | Anti-SLFN14 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-schlafen family member 14 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | ATP binding, SLFN14 and IDBG-304241 and ENSG00000236320 and 342618, SLFN14 and IDBG-630704 and ENSBTAG00000039206 and, Slfn14-ps and IDBG-390973 and ENSMUSG00000082101 and 237890, multiple, this GO :0005524 and ATP binding and molecular function, this GO :0005524: ATP binding, this GO :0005524: ATP binding, schlafen family member 14 |
| Identity | 32689 |
| Gene | SLFN14 |
| Long gene name | schlafen family member 14 |
| Locus | 17q12 |
| Discovery year | 2006-04-05 |
| Entrez gene record | 342618 |
| Pubmed identfication | 9846487 |
| RefSeq identity | NM_001129820 |
| Classification | Schlafen family |
| Havana BLAST/BLAT | OTTHUMG00000179912 |
| Locus Specific Databases | LRG_1114 |