Anti-SLP76 (Polyclonal), ALEXA Fluor 594

Anti-SLP76 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	SLP76
Specificity	This antibody reacts specifically with SLP76
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human SLP76
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Although SLP-76 does not contain a motif that would indicate it to be a member of the tyrosine, However, Overexpression of Vav or SLP-76 in Jurkat cells leads to NFAT activation and IL-2 production, The discovery of SLP-76 represents an important step in elucidating the mechanism of Vav transformation and TCR-mediated NFAT activation, Vav and SLP-76 synergize to induce a robust basal and TCR-mediated IL-2 response, Vav contains a single SH2 domain that is required for its association with the T cell receptor (TCR), When co-expressed, it does contain several putative SH2/SH3-binding domains and has been shown to physically associate with the adapter protein GRB2 as well as PLC g1, serine/threonine or lipid kinase families, the biochemical basis of Vavâ, &euro, &trade, The translational product of the Vav proto-oncogene is exclusively expressed in cells of hematopoietic origin and is critical for lymphocyte development and activation, s function is unclear
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	SLP-76
Also known as	SLP76 Polyclonal Antibody
Other name	Anti-SLP76 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	SLP76
Short name	Anti-SLP76 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-SLP76 (polyclonal)
Alternative technique	polyclonals
Identity	6529
Gene	LCP2
Long gene name	lymphocyte cytosolic protein 2
Synonyms gene	SLP76
Synonyms gene name	lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD) lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
Synonyms name	76 kDa tyrosine phosphoprotein SH2 domain-containing leukocyte protein of 76kD
Locus	5q35, 1
Discovery year	1996-03-12
Entrez gene record	3937
Pubmed identfication	7706237
RefSeq identity	NM_005565
Classification	SH2 domain containing
Havana BLAST/BLAT	OTTHUMG00000163121

Anti-SLP76 (Polyclonal), ALEXA Fluor 594

Anti-SLP76 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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