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Anti-Smad1/5 (Ser463 + Ser465), ALEXA Fluor 594

Anti-Smad1/5 (Ser463 + Ser465), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSmad1/5 Ser463 + Ser465
SpecificitySmad1/5 (Ser463 + Ser465), This phosphorylation site is homologous in the listed cross reactive species at the specified location
ModificationPhosphorylation
Modification siteSer463 + Ser465
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human Smad1/5 around the phosphorylation site of Ser463/465
Gene ID4086, 4090
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Alternatively spliced transcript variants encoding the same protein have been observed, In response to BMP ligands, SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways, The phosphorylated form of this protein forms a complex with SMAD4, This protein is a target for SMAD-specific E3 ubiquitin ligases, This protein mediates the signals of the bone morphogenetic proteins (BMPs), [provided by RefSeq], a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C, and undergoes ubiquitination and proteasome-mediated degradation, apoptosis, development and immune responses, elegans gene Sma, morphogenesis, such as SMURF1 and SMURF2, this protein can be phosphorylated and activated by the BMP receptor kinase, which are involved in a range of biological activities including cell growth, which is important for its function in the transcription regulation, The protein encoded by this gene belongs to the SMAD
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BSP 1, BSP-1, BSP1, Dwarfin A, DwfA, JV 41, JV4 1, JV4-1, JV41, MAD homolog 1, MAD mothers against decapentaplegic homolog 1, MADH 1, MADH1, MADR1, Mad related protein 1, Mad-related protein 1, Madr 1, Mothers against DPP homolog 1, Mothers against DPP homolog 1, Mothers against decapentaplegic homolog 1, Mothers against decapentaplegic homolog 1, SMAD 1, SMAD family member 1, SMAD family member 1, SMAD mothers against DPP homolog 1 Drosophila, SMAD-1, SMAD1_HUMAN, Sma and Mad related protein 1, Smad1, Smad1 phospho Ser463/465, Spinal muscular atrophy distal with upper limb predominance, TGF beta signaling protein 1, Transforming growth factor beta signaling protein 1, Transforming growth factor-beta-signaling protein 1, hSMAD 1, hSMAD1, p-Smad1 Ser463/465, Smad1 phospho S463/465
Also known asSmad1/5 (Ser463 + Ser465) Antibody
Other nameAnti-Smad1/5 (Ser463 + Ser465)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetSmad1/5 (Ser463 + Ser465)
Short nameAnti-Smad1/5 (Ser463 + Ser465) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SMAD family member 1/5 (Ser463 and Ser465)

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