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Anti-Smad2 (Ser465) (Polyclonal), ALEXA Fluor 594

Anti-Smad2 (Ser465) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSmad2 Ser465
SpecificityThis antibody reacts specifically with Smad2 (Ser465)
ModificationPhosphorylation
Modification siteSer465
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human Smad2 around Ser465
Gene ID4087
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It belongs to the SMAD family of proteins, It interacts with SMAD anchor for receptor activation (SARA), It is subsequently transferred to the nucleus where it forms complexes with other proteins and acts as a transcription factor, Like many other TGF-Beta family members SMAD2 is involved in cell signalling, Mothers against DPP homolog 2, SMAD 2, SMAD2 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase, SMAD2 modulates signals of activin and TGF-Beta's, Smad2 (Mothers against decapentaplegic homolog 2, The binding of ligands causes the phosphorylation of the SMAD2 protein and the dissociation from SARA and the association with SMAD4, as its name describes, is a homolog of the Drosophila gene: ", which belong to the TGF-Beta superfamily of modulators, ), Mothers against decepentaplegic", SMAD2 or Mothers against decapentaplegic homolog 2 is a polypeptide that
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms JV18, JV18 1, JV181, MAD, MAD Related Protein 2, MADH2, MADR2, MGC22139, MGC34440, Mothers Against Decapentaplegic Homolog 2, Mothers against DPP homolog 2, Mothers against decapentaplegic homolog 2, SMAD, SMAD 2, SMAD 2, SMAD2, SMAD2_HUMAN, Smad2, Smad2S465, hMAD 2, hSMAD2, mothers against DPP homolog 2, p-Smad2Ser465, Smad2Ser465
Also known asSmad2 (Ser465) Polyclonal Antibody
Other nameAnti-Smad2 (Ser465) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSmad2 (Ser465)
Short nameAnti-Smad2 (Ser465) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SMAD family member 2 (Ser465) (polyclonal)
Alternative techniquepolyclonals

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