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Anti-SMC1 (Polyclonal), ALEXA Fluor 594

Anti-SMC1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSMC1
SpecificityThis antibody reacts specifically with SMC1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human SMC1
Gene ID8243
Swiss ProtQ14683
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information At anaphase, Central component of cohesin complex, Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped, The cohesin complex is required for the cohesion of sister chromatids after DNA replication, The cohesin complex may also play a role in spindle pole assembly during mitosis, Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint, allowing sister chromatids to segregate, or via its phosphorylation by ATR, the complex is cleaved and dissociates from chromatin, Involved in chromosome cohesion during cell cycle and in DNA repair
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms bK268H5
Also known asSMC1 Polyclonal Antibody
Other nameAnti-SMC1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSMC1
Short nameAnti-SMC1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SMC1 (polyclonal)
Alternative techniquepolyclonals
Identity 11112
Gene SMC1B
Long gene name structural maintenance of chromosomes 1B
Synonyms gene SMC1L2
Synonyms gene name SMC1 (structural maintenance of chromosomes 1, yeast)-like 1 SMC1 structural maintenance of chromosomes 1-like 2 (yeast)
Locus 22q13, 31
Discovery year 2000-01-12
GenBank acession AJ504806
Entrez gene record 27127
Pubmed identfication 10591208 11564881
RefSeq identity NM_148674
Classification Structural maintenance of chromosomes proteins Cohesin complex
Havana BLAST/BLAT OTTHUMG00000151334

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