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Anti-SNAIL + SLUG(Ser246) (Polyclonal), ALEXA Fluor 594

Anti-SNAIL + SLUG(Ser246) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSNAIL + SLUG Ser246
SpecificityThis antibody reacts specifically with SNAIL + SLUG(Ser246)
ModificationPhosphorylation
Modification siteSer246
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human SNAIL around the phosphorylation site of Ser246
Gene ID6311
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Mutations in this gene may be associated with sporadic cases of neural tube defects (referenced from Entrez gene), SLUG also has antiapoptotic activity, SLUG is involved in epithelial-mesenchymal transitions (EMT) involving E-cadherin repression which is known to play an important role in tumor progression amd neural tube formation, The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin, This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SNA SLUGH2 SNAH SNAIL1 SNAIL
Also known asSNAIL + SLUG(Ser246) Polyclonal Antibody
Other nameAnti-SNAIL + SLUG(Ser246) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSNAIL + SLUG(Ser246)
Short nameAnti-SNAIL + SLUG(Ser246) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SNAIL and SLUG(Ser246) (polyclonal)
Alternative techniquepolyclonals
Identity 11128
Gene SNAI1
Long gene name snail family transcriptional repressor 1
Synonyms gene name snail 1 (drosophila homolog), zinc finger protein snail homolog 1 (Drosophila) snail family zinc finger 1
Locus 20q13, 13
Discovery year 1998-07-03
GenBank acession AF125377
Entrez gene record 6615
Pubmed identfication 10585766
Classification Zinc fingers C2H2-type SNAG transcriptional repressors
Havana BLAST/BLAT OTTHUMG00000033048

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