Name : Anti-SNAP91/AP180 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4112331045
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SNAP91/AP180 |
| Specificity | This antibody reacts specifically with SNAP91/AP180 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human AP180 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein, The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length, The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly, Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17, a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues, Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA0656 AP180 CALM |
| Also known as | SNAP91/AP180 Polyclonal Antibody |
| Other name | Anti-SNAP91/AP180 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SNAP91/AP180 |
| Short name | Anti-SNAP91/AP180 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | 91kDa homolog (mouse)/AP180 (polyclonal), ALEXA Fluor 594, antibody to-synaptosomal-associated protein |
| Alternative technique | polyclonals |
| Alternative to gene target | 91kDa homolog (mouse), AP180 and CALM, Plasma membranes, SNAP91 and IDBG-630351 and ENSBTAG00000009355 and, SNAP91 and IDBG-93854 and ENSG00000065609 and 9892, Snap91 and IDBG-189699 and ENSMUSG00000033419 and 20616, clathrin binding, this GO :0005515 and protein binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005545 and 1-phosphatidylinositol binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005905 and coated pit and cellular component this GO :0015031 and protein transport and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030118 and clathrin coat and cellular component this GO :0030276 and clathrin binding and molecular function this GO :0048268 and clathrin coat assembly and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005543: phospholipid binding and also this GO :0005545: 1-phosphatidylinositol binding and also this GO :0019901: protein kinase binding and also this GO :0030276: clathrin binding, this GO :0005543: phospholipid binding, this GO :0005545: 1-phosphatidylinositol binding, this GO :0019901: protein kinase binding, this GO :0030276: clathrin binding, synaptosomal-associated protein |
| Identity | 14986 |
| Gene | SNAP91 |
| Long gene name | synaptosome associated protein 91 |
| Synonyms gene name | 91 kDa (mouse) homolog , synaptosomal-associated protein |
| Locus | 6q14, 2 |
| Discovery year | 2001-03-27 |
| GenBank acession | AB014556 |
| Entrez gene record | 9892 |
| Pubmed identfication | 9734811 12493563 10436022 |
| Havana BLAST/BLAT | OTTHUMG00000015114 |