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Anti-SNX2 (Polyclonal), ALEXA Fluor 594

Anti-SNX2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSNX2
SpecificityThis antibody reacts specifically with SNX2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SNX2
Gene ID6643
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Additionally, PDGF and insulin receptor tyrosine kinases, SNX1 and the related splice variant, SNX1A, SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, SNX3, The related protein, These nexins are widely expressed and yet have various tissue distribution patterns, These proteins are all partially associated with cellular membranes and they likewise associate with EGF, as they all contain a characteristic phox homology (PX) domain, bind the epidermal growth factor (EGF) receptor and facilitate its transport to lysosome, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors, suggesting that they exist as part of multi-subunit complexes, the sorting nexins can associate with each other and with a variety of other cellular proteins, thereby contributing to the degradation of the receptor, Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asSNX2 Polyclonal Antibody
Other nameAnti-SNX2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSNX2
Short nameAnti-SNX2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-sorting nexin 2 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BT, Cytoplasm, SNX2 and IDBG-38906 and ENSG00000205302 and 6643, Snx2 and IDBG-146883 and ENSMUSG00000034484 and 67804, TRG-9, phosphatidylinositol binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006886 and intracellular protein transport and biological process this GO :0006897 and endocytosis and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0030904 and retromer complex and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0035091: phosphatidylinositol binding, this GO :0035091: phosphatidylinositol binding, 26946 and IDBG-644960 and ENSBTAG00000025358 and 509769, sorting nexin 2
Identity 11173
Gene SNX2
Long gene name sorting nexin 2
Locus 5q23, 2
Discovery year 1996-07-17
GenBank acession AF043453
Entrez gene record 6643
Pubmed identfication 9819414
RefSeq identity NM_003100
Classification Sorting nexins PX-BAR domain containing
Havana BLAST/BLAT OTTHUMG00000163020

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