Name : Anti-SNX5 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2556384224
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SNX5 |
| Specificity | This antibody reacts specifically with SNX5 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human SNX5 |
| Gene ID | 27131 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Additionally, PDGF and insulin receptor tyrosine kinases (2), SNX1 and the related splice variant, SNX1A, SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, SNX3, The related protein, These nexins are widely expressed and yet have various tissue distribution patterns, These proteins are all partially associated with cellular membranes, and thereby contribute to the degradation of the receptor (2, and they, as they all contain a characteristic phox homology (PX) domain (4), associate with EGF, bind the epidermal growth factor (EGF) receptor, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2, facilitate its transport to lysosome, likewise, suggesting that they exist as part of multisubunit complexes (1, the sorting nexins can associate with each other and with a variety of other cellular proteins, 3), 5), 6), Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1) |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | SNX5 Polyclonal Antibody |
| Other name | Anti-SNX5 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SNX5 |
| Short name | Anti-SNX5 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-SNX5 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 14969 |
| Gene | SNX5 |
| Long gene name | sorting nexin 5 |
| Locus | 20p11, 23 |
| Discovery year | 2001-04-10 |
| GenBank acession | AF121855 |
| Entrez gene record | 27131 |
| Pubmed identfication | 10600472 17148574 |
| Classification | Sorting nexins PX-BAR domain containing |
| Havana BLAST/BLAT | OTTHUMG00000031953 |