Anti-SOCS7 (Polyclonal), Cy3

Anti-SOCS7 (Polyclonal), Cy3 size: 100 microliters 516

Price 516

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	Cy3
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	SOCS7
Specificity	This antibody reacts specifically with SOCS7 Cy3
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Membrane bound, Nucleus, Cytoplasm
Antigen Source	KLH conjugated synthetic peptide derived from human SOCS7
Gene ID	30837
Swiss Prot	O14512
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation, Inhibits also prolactin, May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity), growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA, Regulates signaling cascades probably through protein ubiquitination and/or sequestration
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	512, 550nm/570, 615nm
Also known as	SOCS7 Polyclonal Antibody Cy3
Other name	Anti-SOCS7 Polyclonal Cy3
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	1 of the Anti-SOCS7 (Polyclonal) can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, This Bioss Polyclonal Antibodies antibody is well suited for fluorescent microscopy, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser
Conjugation	cy3 conjugation kit
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	SOCS7
Short name	Anti-SOCS7 (Polyclonal)
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	Cy3
Alternative name	cyanine 3, antibody to-SOCS7 (polyclonal)
Alternative technique	polyclonals
Identity	19392
Gene	SOCS4
Long gene name	suppressor of cytokine signaling 4
Synonyms gene	SOCS7
Synonyms gene name	suppressor of cytokine signaling 7
Locus	14q22, 3
Discovery year	2002-11-11
GenBank acession	AF424815
Entrez gene record	122809
Pubmed identfication	12076535 10500304
Classification	Suppressors of cytokine signaling SH2 domain containing
Havana BLAST/BLAT	OTTHUMG00000140311

Anti-SOCS7 (Polyclonal), Cy3

Anti-SOCS7 (Polyclonal), Cy3 size: 100 microliters 516

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