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Anti-SOD3 (Polyclonal), ALEXA Fluor 594

Anti-SOD3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSOD3
SpecificityThis antibody reacts specifically with SOD3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Secreted, Extracellular
Antigen SourceKLH conjugated synthetic peptide derived from human SOD3
Gene ID6649
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor, SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, SOD1 is found in all eukaryotic species as a homodimeric 32kDa enzyme containing one each of Cu and Zn ion per subunit, SOD3 is a heparin binding multimer of disulfide linked dimers, SOD4 is a copper chaperone for superoxide dismutase(CCS), Several classes of SOD have been identified, The manganese-containing 80kDa tetrameric enzyme SOD2 is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, These include intracellular copper, Zn SOD (EC SOD/SOD3), Zn SOD/SOD1), mitochondrial manganese SOD (Mn SOD/SOD2) and extracellular Cu, primarily expressed in human lungs, the mitochondrial respiratory chain, vessel walls and airways, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase, which specifically delivers Cu to copper/zinc superoxide dismutase, zinc SOD (Cu, Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms EC-SOD
Also known asSOD3 Polyclonal Antibody
Other nameAnti-SOD3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSOD3
Short nameAnti-SOD3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SOD3 (polyclonal)
Alternative techniquepolyclonals
Identity 11181
Gene SOD3
Long gene name superoxide dismutase 3
Synonyms gene name extracellular , superoxide dismutase 3
Locus 4p15, 2
Discovery year 1988-05-08
Entrez gene record 6649
Havana BLAST/BLAT OTTHUMG00000128565

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