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Anti-SORCS1 (Polyclonal), ALEXA Fluor 594

Anti-SORCS1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSORCS1
SpecificityThis antibody reacts specifically with SORCS1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SORCS1
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Alternative splicing of human SorCS1 results in four isoforms with different cytoplasmic tails and differential expression in tissues, Alternative splicing of murine SorCS1 also results in four isoforms, Human SorCS1 is detected in fetal and infant brain and in fetal retina, In the developing and mature central nervous system, It is detected in newborn mouse brain and in adult olfactory bulb and cerebral cortex, Murine isoform 1 is highly expressed in brain and at lower levels in heart, Murine isoform 2 is highly expressed in liver and at lower levels in heart, SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, SorCS1 is a type 1 receptor containing a VPS10P domain and a leucine-rich domain, based on a common VPS10 domain, brain, kidney and testis, liver and kidney, non-overlapping pattern, partially overlapping functions in the central nervous system, the homologous SorCS1 and SorCS2 genes and the SorCS3 gene are expressed in a combinatorial, which is the hallmark of the SorCS receptor family, There are three sorCS genes that have diverse
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms sorCS1
Also known asSORCS1 Polyclonal Antibody
Other nameAnti-SORCS1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSORCS1
Short nameAnti-SORCS1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SORCS1 (polyclonal)
Alternative techniquepolyclonals
Identity 16697
Gene SORCS1
Long gene name sortilin related VPS10 domain containing receptor 1
Synonyms gene name sortilin-related VPS10 domain containing receptor 1
Locus 10q25, 1
Discovery year 2004-04-20
GenBank acession AF284756
Entrez gene record 114815
Pubmed identfication 11499680
RefSeq identity NM_052918
Havana BLAST/BLAT OTTHUMG00000019018

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