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Anti-SorLA (Polyclonal), ALEXA Fluor 594

Anti-SorLA (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSorLA
SpecificityThis antibody reacts specifically with SorLA
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SorLA
Gene ID79845
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Endogenous sorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function, It can also bind to RAP, It is expressed mainly in brain (cerebral cortex, SorLA, SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase, SorLa is a multifunctional endocytis receptor important in lipoprotein and protease uptake, The N-terminal propeptide, a single transmembrane receptor, also known as Sorting protein-related receptor containing LDLR class A (SorLA), binds LDL (the main cholesterol-carrying lipoprotein of plasma) and transports it into cells by endocytosis, but can also be found in liver, can be cleaved by furin or homologous proteases, cerebellum and the occipital pole), is a Type I membrane protein that may be involved in cell-cell interaction, kidney, receptor-associated protein, spinal cord, testis and pancreas, which is removed, Sortilin-related receptor
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms gp250 LR11 LRP9 SorLA SorLA-1
Also known asSorLA Polyclonal Antibody
Other nameAnti-SorLA Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSorLA
Short nameAnti-SorLA (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SorLA (polyclonal)
Alternative techniquepolyclonals
Identity 11185
Gene SORL1
Long gene name sortilin related receptor 1
Synonyms gene C11orf32
Synonyms gene name L(DLR class) A repeats-containing , chromosome 11 open reading frame 32 sortilin-related receptor
Synonyms name LDLR relative with 11 ligand-binding repeats
Locus 11q24, 1
Discovery year 1996-12-27
GenBank acession Y08110
Entrez gene record 6653
Pubmed identfication 9157966 8940146
RefSeq identity NM_003105
Classification Fibronectin type III domain containing
Havana BLAST/BLAT OTTHUMG00000166057

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