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Anti-SOX2 Antibody

Anti-SOX2 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAnti-SOX2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the anti-SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis anti-SOX2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P48431
PurityAntigen affinity
Description Critical for early embryogenesis and for embryonic stem cell pluripotency, Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity), FGF4, Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity), May function as a switch in neuronal development, UTF1 and ZFP206 (By similarity), Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1
ImmunogenThis anti-SOX2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 282-316 amino acids from the C-terminal region of human SOX2
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the anti-SOX2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSOX2
Short nameAnti-SOX2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameantibody to-SRY (sex determining region Y)-box 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ANOP3 and MCOPS3, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0009611 and response to wounding and biological process this GO :0010033 and response to organic substance and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0021781 and glial cell fate commitment and biological process this GO :0021879 and forebrain neuron differentiation and biological process this GO :0021983 and pituitary gland development and biological process this GO :0021984 and adenohypophysis development and biological process this GO :0021987 and cerebral cortex development and biological process this GO :0022409 and positive regulation of cell-cell adhesion and biological process this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030539 and male genitalia development and biological process this GO :0030858 and positive regulation of epithelial cell differentiation and biological process this GO :0030900 and forebrain development and biological process this GO :0030910 and olfactory placode formation and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0035198 and miRNA binding and molecular function this GO :0042246 and tissue regeneration and biological process this GO :0042472 and inner ear morphogenesis and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043586 and tongue development and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044798 and nuclear transcription factor complex and cellular component this GO :0045165 and cell fate commitment and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045747 and positive regulation of Notch signaling pathway and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046148 and pigment biosynthetic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048286 and lung alveolus development and biological process this GO :0048568 and embryonic organ development and biological process this GO :0048646 and anatomical structure formation involved in morphogenesis and biological process this GO :0048663 and neuron fate commitment and biological process this GO :0048839 and inner ear development and biological process this GO :0048852 and diencephalon morphogenesis and biological process this GO :0048863 and stem cell differentiation and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050767 and regulation of neurogenesis and biological process this GO :0050910 and detection of mechanical stimulus involved in sensory perception of sound and biological process this GO :0050973 and detection of mechanical stimulus involved in equilibrioception and biological process this GO :0060042 and retina morphogenesis in camera-type eye and biological process this GO :0060235 and lens induction in camera-type eye and biological process this GO :0060441 and epithelial tube branching involved in lung morphogenesis and biological process this GO :0070848 and response to growth factor and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0097150 and neuronal stem cell maintenance and biological process, SOX2 and IDBG-647279 and ENSBTAG00000011598 and 784383, SOX2 and IDBG-66692 and ENSG00000181449 and 6657, Sox2 and IDBG-137912 and ENSMUSG00000074637 and 20674, nuclei, protein heterodimerization activity, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000976 and transcription regulatory region sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001649 and osteoblast differentiation and biological process this GO :0001654 and eye development and biological process this GO :0001708 and cell fate specification and biological process this GO :0001714 and endodermal cell fate specification and biological process this GO :0002052 and positive regulation of neuroblast proliferation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006325 and chromatin organization and biological process this GO :0006351 and transcription, this GO :0000976: transcription regulatory region sequence-specific DNA binding, this GO :0000976: transcription regulatory region sequence-specific DNA binding and also this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0035198: miRNA binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046982: protein heterodimerization activity, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0035198: miRNA binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0046982: protein heterodimerization activity, SRY (sex determining region Y)-box 2
Identity 11195
Gene SOX2
Long gene name SRY-box 2
Synonyms gene name SRY (sex determining region Y)-box 2 SRY box 2
Locus 3q26, 33
Discovery year 1993-11-30
GenBank acession BC013923
Entrez gene record 6657
Pubmed identfication 7849401
RefSeq identity NM_003106
Classification SRY-boxes
Havana BLAST/BLAT OTTHUMG00000158222
Locus Specific Databases LOVD LRG_719

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