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Anti-SPG21 (Polyclonal), ALEXA Fluor 594

Anti-SPG21 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSPG21
SpecificityThis antibody reacts specifically with SPG21
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SPG21
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Belonging to the AB hydrolase superfamily, Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network, The gene encoding Maspardin is encoded by human chromosome 15, an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs, which houses over 700 genes and comprises nearly 3% of the human genome, Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ACP33 GL010 BM-019 MAST
Also known asSPG21 Polyclonal Antibody
Other nameAnti-SPG21 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSPG21
Short nameAnti-SPG21 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, Mast syndrome) (polyclonal), antibody to-spastic paraplegia 21 (autosomal recessive
Alternative techniquepolyclonals
Alternative to gene target CD4 receptor binding, Mast syndrome), SPG21 and IDBG-16930 and ENSG00000090487 and 51324, SPG21 and IDBG-645311 and ENSBTAG00000011540 and 404069, Spg21 and IDBG-177905 and ENSMUSG00000032388 and 27965, nuclei, this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0008219 and cell death and biological process this GO :0010008 and endosome membrane and cellular component this GO :0030140 and trans- this GO lgi network transport vesicle and cellular component this GO :0042609 and CD4 receptor binding and molecular function this GO :0050851 and antigen receptor-mediated signaling pathway and biological process, this GO :0042609: CD4 receptor binding, this GO :0042609: CD4 receptor binding, spastic paraplegia 21 (autosomal recessive
Identity 20373
Gene SPG21
Long gene name SPG21, maspardin
Synonyms gene name Mast syndrome) , spastic paraplegia 21 (autosomal recessive
Locus 15q22, 31
Discovery year 2004-04-30
GenBank acession AF208861
Entrez gene record 51324
Pubmed identfication 11113139 14564668
RefSeq identity NM_016630
Havana BLAST/BLAT OTTHUMG00000133098

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