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Anti-SPO11 (Polyclonal), ALEXA Fluor 594

Anti-SPO11 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSPO11
SpecificityThis antibody reacts specifically with SPO11
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SPO11
Gene ID23626
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility, Expression of the Spo11 is detected mainly in the testis, The DSBs are located mostly in promoter regions, The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S, and cluster in domains along the chromosome, cerevisiae, in agreement with its predicted function in the initiation of meiotic recombination, where the chromatin is in an open configuration, Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CT35 SPATA43 TOPVIA
Also known asSPO11 Polyclonal Antibody
Other nameAnti-SPO11 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSPO11
Short nameAnti-SPO11 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SPO11 (polyclonal)
Alternative techniquepolyclonals
Identity 11250
Gene SPO11
Long gene name SPO11, initiator of meiotic double stranded breaks
Synonyms gene name SPO11, cerevisiae) SPO11 meiotic protein covalently bound to DSB , cerevisiae) SPO11 meiotic protein covalently bound to DSB homolog (S, cerevisiae)-like SPO11 meiotic protein covalently bound to DSB-like (S, meiotic protein covalently bound to DSB (S
Synonyms name cancer/testis antigen 35 spermatogenesis associated 43
Locus 20q13, 31
Discovery year 1999-12-02
GenBank acession AF169385
Entrez gene record 23626
Pubmed identfication 10534401 26995551
RefSeq identity NM_012444
Havana BLAST/BLAT OTTHUMG00000032817

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