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Anti-SRD5A1 (Polyclonal), ALEXA Fluor 594

Anti-SRD5A1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSRD5A1
SpecificityThis antibody reacts specifically with SRD5A1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human SRD5A1
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 5a-Reductase 1 is expressed in all portions of the hair follicle, 5a-Reductase 1 is mainly expressed in human breast carcinoma and may play a role in the in situ production and actions of the potent androgen 5a-dihydrotestosterone, 5a-Reductase 1 shows heterogeneity of protein, In addition, In cultured human skin cells, The 5a-Reductase-3a-hydroxysteroid dehydrogenase complex is present in the human brain, The enzyme exists as two isoforms: type 1, and has different levels of transcriptional and translational expression, and type 2, including inhibition of cancer cell proliferation in hormone-dependent human breast carcinoma, suggesting that the complex may be involved in the synthesis of neuroactive steroids or the catabolism of neurotoxic steroids, whereas 5a-Reductase 2 is expressed only in mesenchymal portions, which is expressed mainly in the prostate, which is expressed mainly in the skin, which mediates androgen effects on target tissues, Steroid 5a-Reductase is an important enzyme in androgen physiology because it catalyzes the conversion of testosterone into the more potent 5a-dihydro-testosterone
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asSRD5A1 Polyclonal Antibody
Other nameAnti-SRD5A1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSRD5A1
Short nameAnti-SRD5A1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-SRD5A1 (polyclonal)
Alternative techniquepolyclonals
Identity 11284
Gene SRD5A1
Long gene name steroid 5 alpha-reductase 1
Synonyms gene name alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) , steroid-5-alpha-reductase
Synonyms name 3-oxo-5-alpha-steroid 4-dehydrogenase 1
Locus 5p15, 31
Discovery year 1991-05-21
GenBank acession M32313
Entrez gene record 6715
Pubmed identfication 1686016
RefSeq identity NM_001047
Havana BLAST/BLAT OTTHUMG00000090456

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