Name : Anti-SRPX2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6841246871
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | SRPX2 |
| Specificity | This antibody reacts specifically with SRPX2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human SRPX2 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | It has been suggested that SRPX2 enhances cell motility, Localized to the cytoplasm, SRPX2 is a ligand for uPAR (urokinase plasminogen activator), SRPX2 may be responsible for rolandic seizures (RSs) associated with oral and speech dyspraxia and mental retardation (MR), The involvement of SRPX2 in these disorders suggests an important role for SRPX2 in the perisylvian region critical for language and cognitive development, a receptor that is a crucial component of the extracellular plasminogen proteolysis system, including the rolandic area, migration and adhesion through FAK signaling in gastric and other cancer cells, SRPX2 is a 465 amino acid secreted protein expressed in neurons of the brain |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | SRPUL |
| Also known as | SRPX2 Polyclonal Antibody |
| Other name | Anti-SRPX2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | SRPX2 |
| Short name | Anti-SRPX2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, X-linked 2 (polyclonal), antibody to-sushi-repeat containing protein |
| Alternative technique | polyclonals |
| Alternative to gene target | Extracellular, SRPX2 and IDBG-633212 and ENSBTAG00000037686 and 101908743, SRPX2 and IDBG-79192 and ENSG00000102359 and 27286, Srpx2 and IDBG-170434 and ENSMUSG00000031253 and 68792, X-linked 2, identical protein binding, this GO :0001525 and angiogenesis and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0009986 and cell surface and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0030054 and cell junction and cellular component this GO :0036458 and hepatocyte growth factor binding and molecular function this GO :0042325 and regulation of phosphorylation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0048870 and cell motility and biological process this GO :0051965 and positive regulation of synapse assembly and biological process this GO :0060076 and excitatory synapse and cellular component this GO :0071625 and vocalization behavior and biological process this GO :0090050 and positive regulation of cell migration involved in sprouting angiogenesis and biological process this GO :0097060 and synaptic membrane and cellular component, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0036458: hepatocyte growth factor binding and also this GO :0042802: identical protein binding, this GO :0005515: protein binding, this GO :0036458: hepatocyte growth factor binding, this GO :0042802: identical protein binding, 514742, sushi-repeat containing protein |
| Identity | 30668 |
| Gene | SRPX2 |
| Long gene name | X-linked 2 , sushi repeat containing protein |
| Synonyms gene name | X-linked 2 , sushi-repeat-containing protein |
| Locus | Xq22, 1 |
| Discovery year | 2004-06-25 |
| GenBank acession | AF393649 |
| Entrez gene record | 27286 |
| Pubmed identfication | 9864177 |
| RefSeq identity | NM_014467 |
| Classification | Sushi domain containing |
| Havana BLAST/BLAT | OTTHUMG00000022003 |
| Locus Specific Databases | Mental Retardation database |