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Anti-STAT3 Antibody

Anti-STAT3 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAnti-STAT3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the anti-STAT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis anti-STAT3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P40763
PurityAntigen affinity
Description Activated by IL31 through IL31RA, Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes, FGFR2, FGFR3 and FGFR4, KITLG/SCF and other growth factors, May mediate cellular responses to activated FGFR1, Signal transducer and transcription activator that mediates cellular responses to interleukins
ImmunogenA portion of amino acids 683-709 from the human protein was used as the immunogen for this anti-STAT3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the anti-STAT3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSTAT3
Short nameAnti-STAT3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameantibody to-signal transducer and activator on transcription 3 (acute-phase response factor) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ADMIO and APRF and HIES, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006606 and protein import into nucleus and biological process this GO :0006928 and cellular component movement and biological process this GO :0006953 and acute-phase response and biological process this GO :0007165 and signal transduction and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0007399 and nervous system development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010033 and response to organic substance and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016032 and viral process and biological process this GO :0016310 and phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0019953 and sexual reproduction and biological process this GO :0030522 and intracellular receptor signaling pathway and biological process this GO :0031730 and CCR5 chemokine receptor binding and molecular function this GO :0032355 and response to estradiol and biological process this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0034097 and response to cytokine and biological process this GO :0035259 and glucocorticoid receptor binding and molecular function this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0042493 and response to drug and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0042755 and eating behavior and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045471 and response to ethanol and biological process this GO :0045747 and positive regulation of Notch signaling pathway and biological process this GO :0045820 and negative regulation of glycolytic process and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048708 and astrocyte differentiation and biological process this GO :0060019 and radial glial cell differentiation and biological process this GO :0060396 and growth hormone receptor signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0060548 and negative regulation of cell death and biological process this GO :0070102 and interleukin-6-mediated signaling pathway and biological process this GO :2001223 and negative regulation of neuron migration and biological process, STAT3 and IDBG-50702 and ENSG00000168610 and 6774, STAT3 and IDBG-640197 and ENSBTAG00000021523 and 101910056, Stat3 and IDBG-211637 and ENSMUSG00000004040 and 20848, nuclei, protein dimerization activity, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001103 and RNA polymerase II repressing transcription factor binding and molecular function this GO :0001659 and temperature homeostasis and biological process this GO :0001754 and eye photoreceptor cell differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001103: RNA polymerase II repressing transcription factor binding and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0004871: signal transducer activity and also this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0019901: protein kinase binding and also this GO :0019903: protein phosphatase binding and also this GO :0031730: CCR5 chemokine receptor binding and also this GO :0035259: glucocorticoid receptor binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046983: protein dimerization activity, this GO :0001103: RNA polymerase II repressing transcription factor binding, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0004871: signal transducer activity, this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0019901: protein kinase binding, this GO :0019903: protein phosphatase binding, this GO :0031730: CCR5 chemokine receptor binding, this GO :0035259: glucocorticoid receptor binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0046983: protein dimerization activity, 508541, signal transducer and activator of transcription 3 (acute-phase response factor)
Identity 11364
Gene STAT3
Long gene name signal transducer and activator of transcription 3
Synonyms gene name signal transducer and activator of transcription 3 (acute-phase response factor)
Synonyms APRF
Locus 17q21, 2
Discovery year 1995-11-08
GenBank acession BC014482
Entrez gene record 6774
Pubmed identfication 7512451
RefSeq identity NM_139276 NM_003150
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000150645
Locus Specific Databases STAT3base: Mutation registry for Hyper-IgE syndrome LRG_112

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