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Anti-STRA6 (Polyclonal), ALEXA Fluor 594

Anti-STRA6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSTRA6
SpecificityThis antibody reacts specifically with STRA6
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human STRA6
Gene ID64220
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Mutations in the gene encoding Stra6 cause Matthew-Wood Syndrome, Stra6 functions as a cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4), Stra6 is broadly expressed, Stra6 removes retinol from RBP/RPB4 and transports it across the plasma membrane, The Stra6 gene maps to chromosome 15q24, This syndrome is characterized by anophtalmia, Ultimately increasing cellular retinol uptake from the retinol-RBP complex, also known as Spear Syndrome, lung and diaphragm, mild facial dysmorphism and malformations of the heart, multi-pass cell membrane protein, where it is metabolized, with 4 named isoforms that exist as a result of alternative splicing events, 1, STRA6 is a 667 amino acid
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ12541
Also known asSTRA6 Polyclonal Antibody
Other nameAnti-STRA6 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSTRA6
Short nameAnti-STRA6 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-STRA6 (polyclonal)
Alternative techniquepolyclonals
Identity 30650
Gene STRA6
Long gene name stimulated by retinoic acid 6
Synonyms gene name stimulated by retinoic acid gene 6 homolog (mouse) stimulated by retinoic acid 6 homolog (mouse)
Synonyms name retinol binding protein 4 receptor
Locus 15q24, 1
Discovery year 2004-12-20
GenBank acession AF352728
Entrez gene record 64220
Pubmed identfication 17255476 17273977
Havana BLAST/BLAT OTTHUMG00000138998
Locus Specific Databases LOVD

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