Filters

Anti-Supervillin (Polyclonal), ALEXA Fluor 594

Anti-Supervillin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSupervillin
SpecificityThis antibody reacts specifically with Supervillin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCell membrane
Antigen SourceKLH conjugated synthetic peptide derived from human Supervillin
Gene ID6840
Swiss ProtO95425
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Appears to be involved in myosin II assembly, Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation, Isoform 2 may be involved in modulation of focal adhesions, May modulate myosin II regulation through MLCK during cell spreading, May play a role in invadopodial function, Plays a role in cytokinesis through KIF14 interaction (By similarity), Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6, an initial step in cell migration, Forms a high-affinity link between the actin cytoskeleton and the membrane
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asSupervillin Polyclonal Antibody
Other nameAnti-Supervillin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSupervillin
Short nameAnti-Supervillin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Supervillin (polyclonal)
Alternative techniquepolyclonals
Identity 11480
Gene SVIL
Long gene name supervillin
Synonyms name archvillin
Locus 10p11, 23
Discovery year 1998-05-07
GenBank acession AF051851
Entrez gene record 6840
Pubmed identfication 9382871
Classification Gelsolin/villins
Havana BLAST/BLAT OTTHUMG00000017882

Similar products

Subscribe to our Newsletter