Anti-SV2C (Polyclonal), ALEXA Fluor 594

Anti-SV2C (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	SV2C
Specificity	This antibody reacts specifically with SV2C
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from human SV2C
Gene ID	22987
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	SV2 proteins are abundant, SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, SV2A and SV2B, SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates, SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation, SV2A is abundantly expressed in the subcortex, SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex, SV2C, and also in most neuroendocrine secretory granules, and one minor isoform, hydrophobic, independent of transmitter type, membrane glycoproteins that are expressed as two major isoforms, specifically in the synaptic vesicles of all presynaptic nerve terminals, In all vertebrates
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Also known as	SV2C Polyclonal Antibody
Other name	Anti-SV2C Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	SV2C
Short name	Anti-SV2C (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-SV2C (polyclonal)
Alternative technique	polyclonals
Identity	30670
Gene	SV2C
Long gene name	synaptic vesicle glycoprotein 2C
Locus	5q13, 3
Discovery year	2004-04-01
GenBank acession	AB028977
Entrez gene record	22987
Pubmed identfication	10470851 9801366
Havana BLAST/BLAT	OTTHUMG00000162384

Anti-SV2C (Polyclonal), ALEXA Fluor 594

Anti-SV2C (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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