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Anti-Synaptotagmin XI (Polyclonal), ALEXA Fluor 594

Anti-Synaptotagmin XI (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideSynaptotagmin XI
SpecificityThis antibody reacts specifically with Synaptotagmin XI
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Synaptotagmin XI
Gene ID23208
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, Like other Synaptotagmin proteins, Synaptotagmin XI, Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinsonâ, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking, also known as SYT11 (Synaptotagmin-11), including schizophrenia and Parkinsonâ, is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung, the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex, &euro, &euro, &trade, &trade, Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles, s disease, s disease gene product)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA0080 MGC10881 MGC17226 DKFZp781D015
Also known asSynaptotagmin XI Polyclonal Antibody
Other nameAnti-Synaptotagmin XI Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetSynaptotagmin XI
Short nameAnti-Synaptotagmin XI (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Synaptotagmin XI (polyclonal)
Alternative techniquepolyclonals
Identity 19239
Gene SYT11
Long gene name synaptotagmin 11
Synonyms gene name synaptotagmin XI
Locus 1q22
Discovery year 2002-09-20
GenBank acession D38522
Entrez gene record 23208
Pubmed identfication 11543631
RefSeq identity NM_152280
Classification Synaptotagmins
Havana BLAST/BLAT OTTHUMG00000014105

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