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Anti-TBCE (Polyclonal), ALEXA Fluor 594

Anti-TBCE (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTBCE
SpecificityThis antibody reacts specifically with TBCE
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human TBCE
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Biosynthesis of functional microtubules involve the participation of several chaperones, D (TBCD), E (TBCE) and C (TBCC), KCS, KCS1 or pac2, Mutations in the gene encoding TBCE are the cause of hypoparathyroidism-retardation-dysmorphism syndrome and Kenny-Caffey syndrome type 1, TBCE (tubulin folding cofactor E), TBCE associates with microtubules and proteasomes, TBCE is involved in the second step of the Tubulin folding pathway and is implicated in the maintenance of the neuronal microtubule network, also known as HRD, alternatively named TCP, and protects against misfolded protein stress, are highly dynamic structures composed of Alpha/Beta Tubulin heterodimers, is a 527 amino acid cytoplasmic protein containing one CAP-Gly domain and seven LRR (leucine-rich) repeats, termed Tubulin folding cofactors A (TBCA), that act on folding intermediates downstream of the cytosolic chaperon, the primary component of the cytoskeletal network, Microtubules
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KCS1 pac2
Also known asTBCE Polyclonal Antibody
Other nameAnti-TBCE Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTBCE
Short nameAnti-TBCE (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TBCE (polyclonal)
Alternative techniquepolyclonals
Identity 11582
Gene TBCE
Long gene name tubulin folding cofactor E
Synonyms gene KCS HRD
Synonyms gene name and dysmorphism , growth and mental retardation, tubulin-specific chaperone e Kenny-Caffey syndrome hypoparathyroidism
Locus 1q42, 3
Discovery year 1998-07-31
GenBank acession U61232
Entrez gene record 6905
Pubmed identfication 8706133 9806825 12389028
RefSeq identity NM_003193
Havana BLAST/BLAT OTTHUMG00000039987

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