Name : Anti-TEM1/CD248 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3891857998
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | TEM1/CD248 |
| Specificity | This antibody reacts specifically with TEM1/CD248 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human TEM 1 |
| Gene ID | 57124 |
| Swiss Prot | Q9HCU0 |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | It is believed to play a role in tumor angiogenesis, It is expressed in stromal fibroblasts, TEM1 is being investigated as a potential target for cancer treatment, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing, The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | TEM1 |
| Also known as | TEM1/CD248 Polyclonal Antibody |
| Other name | Anti-TEM1/CD248 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | TEM1/CD248 |
| Short name | Anti-TEM1/CD248 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, endosialin (polyclonal), antibody to-TEM1/CD248 molecule |
| Alternative technique | polyclonals |
| Alternative to gene target | CD248 and IDBG-58835 and ENSG00000174807 and 57124, CD248 and IDBG-644374 and ENSBTAG00000044073 and 520070, Cd248 and IDBG-130731 and ENSMUSG00000056481 and 70445, Extracellular, endosialin, extracellular matrix binding, this GO :0003674 and molecular function and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0008150 and biological process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0030246 and carbohydrate binding and molecular function this GO :0048535 and lymph node development and biological process this GO :0050840 and extracellular matrix binding and molecular function this GO :0060033 and anatomical structure regression and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0003674: molecular_function, this GO :0003674: molecular_function and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0030246: carbohydrate binding and also this GO :0050840: extracellular matrix binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0030246: carbohydrate binding, this GO :0050840: extracellular matrix binding, CD248 molecule |
| Identity | 18219 |
| Gene | CD248 |
| Long gene name | CD248 molecule |
| Synonyms gene | CD164L1 |
| Synonyms gene name | CD164 sialomucin-like 1 CD248 antigen, endosialin , endosialin CD248 molecule |
| Synonyms name | endosialin tumor endothelial marker 1 |
| Locus | 11q13, 2 |
| Discovery year | 2003-08-27 |
| GenBank acession | AF279142 |
| Entrez gene record | 57124 |
| Pubmed identfication | 10947988 11084048 |
| RefSeq identity | NM_020404 |
| Classification | CD molecules C-type lectin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000167073 |