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Anti-TEM1/CD248 (Polyclonal), ALEXA Fluor 594

Anti-TEM1/CD248 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTEM1/CD248
SpecificityThis antibody reacts specifically with TEM1/CD248
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human TEM 1
Gene ID57124
Swiss ProtQ9HCU0
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It is believed to play a role in tumor angiogenesis, It is expressed in stromal fibroblasts, TEM1 is being investigated as a potential target for cancer treatment, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing, The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms TEM1
Also known asTEM1/CD248 Polyclonal Antibody
Other nameAnti-TEM1/CD248 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTEM1/CD248
Short nameAnti-TEM1/CD248 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, endosialin (polyclonal), antibody to-TEM1/CD248 molecule
Alternative techniquepolyclonals
Alternative to gene target CD248 and IDBG-58835 and ENSG00000174807 and 57124, CD248 and IDBG-644374 and ENSBTAG00000044073 and 520070, Cd248 and IDBG-130731 and ENSMUSG00000056481 and 70445, Extracellular, endosialin, extracellular matrix binding, this GO :0003674 and molecular function and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0008150 and biological process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0030246 and carbohydrate binding and molecular function this GO :0048535 and lymph node development and biological process this GO :0050840 and extracellular matrix binding and molecular function this GO :0060033 and anatomical structure regression and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0003674: molecular_function, this GO :0003674: molecular_function and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0030246: carbohydrate binding and also this GO :0050840: extracellular matrix binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0030246: carbohydrate binding, this GO :0050840: extracellular matrix binding, CD248 molecule
Identity 18219
Gene CD248
Long gene name CD248 molecule
Synonyms gene CD164L1
Synonyms gene name CD164 sialomucin-like 1 CD248 antigen, endosialin , endosialin CD248 molecule
Synonyms name endosialin tumor endothelial marker 1
Locus 11q13, 2
Discovery year 2003-08-27
GenBank acession AF279142
Entrez gene record 57124
Pubmed identfication 10947988 11084048
RefSeq identity NM_020404
Classification CD molecules C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000167073

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