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Anti-TGF Beta R3 (Polyclonal), ALEXA Fluor 594

Anti-TGF Beta R3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTGF Beta R3
SpecificityThis antibody reacts specifically with TGF Beta R3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human TGFBR3
Gene ID7049
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII, It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form, It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems, Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2, TGF beta III receptor, TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor, TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone, TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling, TGFB2, The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins, There are 3 forms encoded by separate genes TGFB1, These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, adhesion, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration, and TGFB3, and extracellular matrix production, can function as an inhibin coreceptor with ActRII, cell cycle progression, cellular migration, including cell differentiation, nonredundant role in TGF beta signaling, or beta glycan, type III (TGF beta III receptor) has been identified, Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BGCAN, Betaglycan, Betaglycan proteoglycan, TGF beta Receptor III, TGF beta receptor type 3, TGF beta receptor type III, TGFB R3, TGFBR 3, TGFBR3, TGFR 3, TGFR3, Transforming Growth Factor Beta Receptor III, Transforming growth factor beta receptor III betaglycan 300kDa, Beta glycan
Also known asTGF Beta R3 Polyclonal Antibody
Other nameAnti-TGF Beta R3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTGF Beta R3
Short nameAnti-TGF Beta R3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TGF b R3 (polyclonal)
Alternative techniquepolyclonals

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