Name : Anti-THAP1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4833103591
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | THAP1 |
| Specificity | This antibody reacts specifically with THAP1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human THAP1 |
| Gene ID | 55145 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | It colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies and is a pro-apoptopic protein that potentiates both serum-withdrawal and TNF-induced apoptosis, It is a physiologic regulator of endothelial cell proliferation and cell-cycle progression, a zinc-dependent DNA-binding domain, two essential processes for angiogenesis, THAP1 contains a THAP domain |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ10477 4833431A01Rik |
| Also known as | THAP1 Polyclonal Antibody |
| Other name | Anti-THAP1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | THAP1 |
| Short name | Anti-THAP1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, apoptosis associated protein 1 (polyclonal), antibody to-THAP domain containing |
| Alternative technique | polyclonals |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007049 and cell cycle and biological process this GO :0007346 and regulation of mitotic cell cycle and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016605 and PML body and cellular component this GO :0043565 and sequence-specific DNA binding and molecular function, THAP1 and IDBG-20415 and ENSG00000131931 and 55145, THAP1 and IDBG-629979 and ENSBTAG00000007629 and 538615, Thap1 and IDBG-145273 and ENSMUSG00000037214 and 73754, apoptosis associated protein 1, nuclei, sequence-specific DNA binding, this GO :0001935 and endothelial cell proliferation and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003676: nucleic acid binding, this GO :0003676: nucleic acid binding and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0043565: sequence-specific DNA binding, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0043565: sequence-specific DNA binding, THAP domain containing |
| Identity | 20856 |
| Gene | THAP1 |
| Long gene name | THAP domain containing 1 |
| Synonyms gene | DYT6 |
| Synonyms gene name | apoptosis associated protein 1 , dystonia 6, torsion (autosomal dominant) THAP domain containing |
| Locus | 8p11, 21 |
| Discovery year | 2003-07-21 |
| GenBank acession | BC021721 |
| Entrez gene record | 55145 |
| Pubmed identfication | 12575992 12717420 19182804 |
| RefSeq identity | NM_018105 |
| Classification | THAP domain containing |
| Havana BLAST/BLAT | OTTHUMG00000165276 |