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Anti-Thioredoxin 2 (Polyclonal), ALEXA Fluor 594

Anti-Thioredoxin 2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideThioredoxin 2
SpecificityThis antibody reacts specifically with Thioredoxin 2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Thioredoxin 2
Gene ID25828
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information NF-kB and AP-1, Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor, Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, The reduced Trx is a hydrogen donor for ribonucleotide reductase, The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds, Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site, Trx is also capable of removing H2O2, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins, the essential enzyme for DNA synthesis, Thioredoxins (Trx) are small
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SPTRX1
Also known asThioredoxin 2 Polyclonal Antibody
Other nameAnti-Thioredoxin 2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetThioredoxin 2
Short nameAnti-Thioredoxin 2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Thioredoxin 2 (polyclonal)
Alternative techniquepolyclonals
Identity 16470
Gene TXNDC2
Long gene name thioredoxin domain containing 2
Synonyms gene name thioredoxin domain containing 2 (spermatozoa)
Synonyms name sperm-specific thioredoxin 1
Locus 18p11, 2 , 31-p11
Discovery year 2001-08-30
GenBank acession AF080095
Pubmed identfication 11230166 11399755
Havana BLAST/BLAT OTTHUMG00000131602

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