Anti-THOC2 (Polyclonal), ALEXA Fluor 594

Anti-THOC2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	THOC2
Specificity	This antibody reacts specifically with THOC2
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Nucleus
Antigen Source	KLH conjugated synthetic peptide derived from human THOC2
Gene ID	57187
Swiss Prot	Q8NI27
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, Required for NXF1 localization to the nuclear rim, THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains, TREX is recruited to spliced mRNAs by a transcription-independent mechanism, The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway, processing and nuclear export, Required for efficient export of polyadenylated RNA and spliced mRNA
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	THO2 dJ506G2, 1
Also known as	THOC2 Polyclonal Antibody
Other name	Anti-THOC2 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	THOC2
Short name	Anti-THOC2 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-THOC2 (polyclonal)
Alternative technique	polyclonals
Identity	19073
Gene	THOC2
Long gene name	THO complex 2
Synonyms gene	CXorf3 MRX12 MRX35
Synonyms gene name	X-linked 12 mental retardation, X-linked 35 , chromosome X open reading frame 3 mental retardation
Locus	Xq25
Discovery year	2002-12-09
GenBank acession	AF441770
Entrez gene record	57187
Pubmed identfication	11979277 15998806 26166480
Classification	X-linked mental retardation THO complex
Havana BLAST/BLAT	OTTHUMG00000022334
Locus Specific Databases	Mental Retardation database

Anti-THOC2 (Polyclonal), ALEXA Fluor 594

Anti-THOC2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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