Name : Anti-Thyroid Hormone Receptor beta, ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8599483935
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | THRB1/Thyroid Hormone Receptor beta |
| Specificity | This antibody reacts specifically with Thyroid Hormone Receptor beta |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Thyroid Hormone Receptor beta |
| Gene ID | 7068 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Defects in the receptor result in generalized thyroid hormone resistance (GTHR), GTHR is transmitted as an autosomal dominant trait, GTHR patients also have high levels of circulating thyroid hormones (T3-T4), It is composed of three domains: a modulating N-terminal domain, The disease is characterized by goiter, Thyroid hormone receptor b2 (TRb2) is a high affinity receptor for triiodothyronine which belongs to the nuclear hormone receptor family and the NR1 subfamily, a DNA-binding domain and a C-terminal steroid-binding domain, abnormal growth and bone maturation, abnormal mental functions, but an autosomal recessive form also exists, increased susceptibility to infections, tachycardia and deafness, with normal or slightly elevated thyroid stimulating hormone, Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate the biological activities of thyroid hormone (T3) |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | Avian erythroblastic leukemia viral v erb a oncogene homolog 2, C ERBA 2, C ERBA BETA, ERBA 2, ERBA BETA, ERBA2, Erythroblastic leukemia viral v erb a oncogene homolog 2 avian, GRTH, MGC126109, MGC126110, NR1A2, Nuclear receptor subfamily 1 group A member 2, Oncogene ERBA2, PRTH, THB_HUMAN, THR 1, THR1, THRB, THRB 1, THRB 2, THRB1, THRB2, Thyroid hormone nuclear receptor beta variant 1, Thyroid hormone receptor, Thyroid hormone receptor beta, Thyroid hormone receptor beta 1, Thyroid hormone receptor beta 2, avian, beta erythroblastic leukemia viral v erb a oncogene homolog 2, c-erbA-2, c-erbA-beta, generalized resistance to thyroid hormone, Thyroid Hormone Receptor beta |
| Also known as | Thyroid Hormone Receptor beta Antibody |
| Other name | Anti-Thyroid Hormone Receptor beta |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Description | FSH comprise the , Human recombinant LHRG and GHRH are produced in E, The glands that secrete Luteinizing hormones LHRG and LH, The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine , coli or in yeast cells, Hormone releasing factors and releasing hormones are  , endocrine signaling system, glands , in , intracrine signaling) or nearby cells (paracrine signaling), multicellular organisms, or , produced by , signaling molecules  |
| Gene target | Thyroid Hormone Receptor beta |
| Short name | Fluor 594, Anti-Thyroid Hormone Receptor beta |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Thyroid Hormone Receptor b |